Latest List of NIH Funding Grants
Here is the recent list of 100 Grants from NIH
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)
Notice Number:
Funding Instrument:
Grant
Funding Category:
Research and Development
Activity Code:
Planning Grant (R34)
Purpose: The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions. Existing data suggest that significant acute and chronic disease inequities exist for NA populations. Concurrently, NA populations experience unique sociopolitical, historical, and environmental stressors and risks that may exacerbate health conditions and/or impact the effectiveness of existing solutions to address the conditions. They also possess unique strengths and resiliencies that can mitigate stressors or inform intervention strategies. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to test science-based, culturally appropriate solutions to reduce morbidity and mortality through identification and remediation of precursors to diseases and disorders and through culturally informed treatment. Interventions should be designed with a consideration for sustainability within the communities where they are tested, and have the flexibility to be readily adapted, disseminated, and scaled up to other communities where culturally appropriate. For the purposes of this NOFO, NA includes the following populations: Alaska Natives, American Indians (whose ancestral lands fall at least partially within the U.S. main land).
Issuing Organization:
NIDA
Participating Organization(s):
NCCIH, NIA, NIAAA, NICHD, NIDCR, NIEHS, NIMH, NINR, OBSSR, ODP, ORWH, THRO
Application Types Allowed:
New, Resubmission
Release Date:
January 22, 2025
Expiration Date:
January 8, 2027
Clinical Trials:
Optional
New Investigator Gateway Awards for Collaborative T1D Research (R03 Clinical Trial Not Allowed)
Notice Number:
Funding Instrument:
Grant
Funding Category:
Research and Development
Activity Code:
Small Research Grants (R03)
Purpose: The New Investigator Gateway Award in T1D Research is designed to supporta robust pipeline of innovative projects and talented new investigators in T1D research. In addition to providing support for preliminary research, the Gateway program provides an opportunity for new Program Directors/Principal Investigators (PD/PIs) to pursue their studies within the intellectual environment of a select number of large, ongoing collaborative research programs. Embedding awardees within an established scientific framework in each of these consortia will provide unique opportunities for New andEarly Stage Investigators to increase their understanding of key questions in the field, to network, and to establish unique and potentially long-lasting collaborations that will propel their careers forward. Bringing New and Early Stage Investigators into existing collaborative research networks will also benefit the networks by providing new ideas and perspectives.
Issuing Organization:
NIDDK
Participating Organization(s):
OD
Application Types Allowed:
New, Resubmission
Release Date:
January 22, 2025
Expiration Date:
March 7, 2026
Clinical Trials:
Not Allowed
Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)
Notice Number:
Funding Instrument:
Grant
Funding Category:
Research Training and Career Development
Activity Code:
Education Projects (R25)
Purpose: The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on: Courses for Skills Development
Issuing Organization:
OBSSR
Participating Organization(s):
NCCIH, NCI, NHLBI, NIDA, NIDCD, NIDCR, NIDDK, NIMH, NINR, ODP, ODS, ORWH
Application Types Allowed:
New, Renewal, Resubmission, Revision
Release Date:
January 21, 2025
Expiration Date:
April 10, 2027
Clinical Trials:
Not Allowed
Career Stage:
Established Investigator
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)
Notice Number:
Funding Instrument:
Grant
Funding Category:
Research and Development
Activity Code:
Research Project (R01)
Purpose: The purpose of this funding opportunity announcement (FOA) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions. Existing data suggest that significant acute and chronic disease inequities exist for NA populations. Concurrently, NA populations experience unique sociopolitical, historical, and environmental stressors and risks that may exacerbate health conditions and/or impact the effectiveness of existing solutions to address the conditions. They also possess unique strengths and resiliencies that can mitigate stressors or inform intervention strategies. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to test science-based, culturally appropriate solutions to reduce morbidity and mortality through identification and remediation of precursors to diseases and disorders and through culturally informed treatment. Interventions should be designed with a consideration for sustainability within the communities where they are tested, and have the flexibility to be readily adapted, disseminated, and scaled up to other communities where culturally appropriate. For the purposes of this FOA, Native Americans include the following populations: Alaska Natives, American Indians (whose ancestral lands fall at least partially within the U.S. ma
Issuing Organization:
NIDA
Participating Organization(s):
NCI, NHLBI, NIA, NIAAA, NIAID, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIEHS, NIMH, NIMHD, NINR, NLM, OBSSR, ODP, ORWH, THRO
Application Types Allowed:
New, Renewal, Resubmission, Revision
Release Date:
January 21, 2025
Expiration Date:
January 8, 2027
Clinical Trials:
Optional
Laboratory Flexible Funding Model (LFFM)
Notice Number:
Funding Instrument:
Cooperative Agreements
Funding Category:
Research and Development
Activity Code:
Research Program--Cooperative Agreements (U19)
Purpose: This cooperative agreement is intended to enhance the capacity and capabilities of state human and animal food testing laboratories in support of an integrated food safety system (IFSS). This is achieved through prioritized sample testing and food defense preparedness in the areas of microbiology, chemistry, and radiochemistry, as well as method development and capacity/capability development projects that support and expand food safety and food defense testing.
Issuing Organization:
FDA
Application Types Allowed:
New
Release Date:
January 17, 2025
Expiration Date:
January 11, 2028
Clinical Trials:
Not Allowed
Leadership and Coordination Center (LACC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)
Notice Number:
Funding Instrument:
Cooperative Agreements
Funding Category:
Research and Development
Activity Code:
Research Project--Cooperative Agreements (U01)
Purpose: The purpose of this Notice of Funding Opportunity (NOFO) is to renew the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 6-year project period (2026-2032). Continuation of this epidemiological cohort study of middle-aged and older people living with HIV (PLWH), along with comparable individuals living without HIV (PLWOH) will enable the continued follow-up of a deeply phenotyped cohort of approximately 5,600 participants from across the United States. This initiative will utilize a populomics approach, i.e., examination of health determinants across multiple scales of influence (e.g. molecular, cellular, physiological, lifestyle/behavioral, household, neighborhood, environmental, cultural, and sociopolitical) using multi-disciplinary methods to investigate the web of influences impacting the health, quality of life, and survival of adults living with HIV. This NOFO seeks applications to fund a single Leadership and Coordination Center (LACC) for the MWCCS. This NOFO runs in parallel with two companion U01 NOFOs: RFA-HL-26-009 (Limited Competition: Clinical Research Sites (CRS) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)) and RFA-HL-26-010 (Limited Competition: Data Analysis and Sharing Center (DASC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed))
Issuing Organization:
NHLBI
Participating Organization(s):
NCI, NIA, NIAAA, NIAID, NICHD, NIDA, NIDCD, NIDCR, NIMH, NIMHD, NINR, ORWH
Application Types Allowed:
New
Release Date:
January 16, 2025
Expiration Date:
May 3, 2025
Clinical Trials:
Not Allowed
Limited Competition: Data Analysis and Sharing Center (DASC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)
Notice Number:
Funding Instrument:
Cooperative Agreements
Funding Category:
Research and Development
Activity Code:
Research Project--Cooperative Agreements (U01)
Purpose: The purpose of this Notice of Funding Opportunity (NOFO) is to renew the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 7-year project period (2026-2033). Continuation of this epidemiological cohort study of middle-aged and older people living with HIV (PLWH), along with comparable individuals living without HIV (PLWOH) will enable the continued follow-up of a deeply phenotyped cohort of approximately 5,500 participants from across the United States. This initiative will utilize a populomics approach, i.e., examination of health determinants across multiple scales of influence (e.g. molecular, cellular, physiological, lifestyle/behavioral, household, neighborhood, environmental, cultural, and sociopolitical) using multi-disciplinary methods to investigate the web of influences impacting the health, quality of life, and survival of adults living with HIV. This NOFO seeks applications to fund a single Data Analysis and Sharing Center (DASC) for the MWCCS, with competition limited to institutions who were funded under RFA-HL-19-007.
Issuing Organization:
NHLBI
Participating Organization(s):
NCI, NIA, NIAAA, NIAID, NICHD, NIDA, NIDCD, NIDCR, NIMH, NIMHD, NINR, ORWH
Application Types Allowed:
New, Renewal
Release Date:
January 16, 2025
Expiration Date:
May 3, 2025
Clinical Trials:
Not Allowed
Limited Competition: Clinical Research Sites (CRS) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trial Not Allowed)
Notice Number:
Funding Instrument:
Cooperative Agreements
Funding Category:
Research and Development
Activity Code:
Research Project--Cooperative Agreements (U01)
Purpose: The purpose of this Notice of Funding Opportunity (NOFO) is to renew the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 6-year project period (2026-2032). Continuation of this epidemiological cohort study of middle-aged and older people living with HIV (PLWH), along with comparable people living without HIV (PLWOH) will enable the continued follow-up of a deeply phenotyped cohort of more than 5,600 participants from across the United States. This initiative will utilize a populomics approach, i.e., examination of health determinants across multiple scales of influence (e.g. molecular, cellular, physiological, lifestyle/behavioral, household, neighborhood, environmental, cultural, and sociopolitical) using multi-disciplinary methods to investigate the web of influences impacting the health, quality of life, and survival of adults living with HIV. This NOFO is limited to institutions who were funded under RFA-HL-19-008 and will fund up to 13 Clinical Research Sites (CRS) for the MWCCS. This NOFO runs in parallel with two companion U01 NOFOs: RFA-HL-26-010 (Limited Competition: Data Analysis and Sharing Center (DASC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)) and RFA-HL-26-011 (Leadership and Coordination Center (LACC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)).
Issuing Organization:
NHLBI
Participating Organization(s):
NCI, NIA, NIAAA, NIAID, NICHD, NIDA, NIDCD, NIDCR, NIMH, NIMHD, NINR, ORWH
Application Types Allowed:
New, Renewal
Release Date:
January 16, 2025
Expiration Date:
May 3, 2025
Clinical Trials:
Not Allowed
Asthma and Allergic Diseases Cooperative Research Centers (U19 Clinical Trial Optional)
Notice Number:
Funding Instrument:
Cooperative Agreements
Funding Category:
Research and Development
Activity Code:
Research Program--Cooperative Agreements (U19)
Purpose: The purpose of this notice of funding opportunity (NOFO) is to invite applications from single institutions or consortia of institutions to participate in the Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program. The program will support centers that integrate clinical and translational research to conduct studies on the mechanisms underlying the onset and progression of diseases of interest, including asthma, rhinitis (allergic and non-allergic), chronic rhinosinusitis, atopic dermatitis, food allergy, and drug allergy. The overarching goal of the program is to improve the understanding of the pathogenesis of these conditions and to provide a rational foundation for new, effective treatments and prevention strategies.
Issuing Organization:
NIAID
Application Types Allowed:
New, Renewal
Release Date:
January 16, 2025
Expiration Date:
June 14, 2025
Clinical Trials:
Optional
Collaborative Research Using Biosamples and/or Data from Type 1 Diabetes Clinical Studies (R01 - Clinical Trial Not Allowed)
Notice Number:
Funding Instrument:
Grant
Funding Category:
Research and Development
Activity Code:
Research Project (R01)
Purpose: This Notice of Funding Opportunity (NOFO) invites applications for studies of type 1 diabetes etiology and pathogenesis using data and samples from clinical trials and studies. This opportunity is intended to fund investigative teams collaborating to answer important questions about disease mechanisms leading to improved prevention of type 1 diabetes.
Issuing Organization:
NIDDK
Participating Organization(s):
OD
Application Types Allowed:
New, Resubmission
Release Date:
January 15, 2025
Expiration Date:
March 9, 2026
Clinical Trials:
Not Allowed
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U19 Clinical Trial Optional)
Notice Number:
Funding Instrument:
Cooperative Agreements
Funding Category:
Research and Development
Activity Code:
Research Program--Cooperative Agreements (U19)
Purpose: Reissue of PAR-20-119. This FOA encourages applications to advance the discovery, preclinical development, and proof of concept (PoC) testing of new, rationally based candidate agents and neurostimulation approaches to treat mental disorders, substance use disorders (SUDs) or alcohol use disorder (AUD), and to develop novel ligands and circuit-engagement devices as tools to further characterize existing or to validate new drug/device targets. Partnerships between academia and industry are strongly encouraged. This FOA supports a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach. Projects seeking support for a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies should consider the companion U01 FOA.
Issuing Organization:
NIMH
Application Types Allowed:
New, Renewal, Resubmission, Revision
Release Date:
January 15, 2025
Expiration Date:
October 26, 2027
Clinical Trials:
Optional
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01 Clinical Trial Optional)
Notice Number:
Funding Instrument:
Cooperative Agreements
Funding Category:
Research and Development
Activity Code:
Research Project--Cooperative Agreements (U01)
Purpose: Reissue of PAR-20-118. This Notice of Funding Opportunity (NOFO) encourages applications to advance the discovery, preclinical development, and proof of concept (PoC) testing of new, rationally based candidate agents and neurostimulation approaches to treat mental disorders, substance use disorders (SUDs) or alcohol use disorder (AUD), and to develop novel ligands and circuit-engagement devices as tools to further characterize existing or to validate new drug/device targets. Partnerships between academia and industry are strongly encouraged. This NOFO using the U01 mechanism supports a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies Projects seeking support for a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach should consider the companion U19 FOA.
Issuing Organization:
NIMH
Application Types Allowed:
New, Renewal, Resubmission, Revision
Release Date:
January 15, 2025
Expiration Date:
October 26, 2027
Clinical Trials:
Optional
NCI Pathway to Independence Award (K99/R00 Clinical Trial Required)
Notice Number:
Funding Instrument:
Grant
Funding Category:
Research Training and Career Development, Research and Development
Activity Code:
Career Transition Award (K99), Research Transition Award (R00)
Purpose: The purpose of the NCI Pathway to Independence Award (K99/R00) program is to facilitate a timely transition of talented postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NCI research support during this transition in order to help awardees to launch competitive, independent research careers.
Issuing Organization:
NCI
Application Types Allowed:
New, Resubmission
Release Date:
January 14, 2025
Expiration Date:
October 15, 2027
Clinical Trials:
Required
PD/PI US Citizenship Requirement:
Yes
Career Stage:
Early Career
Mentored:
Yes
Molecular Mechanisms of Combination Adjuvants (MMCA) (R01 Clinical Trial Not Allowed)
Notice Number:
Funding Instrument:
Grant
Funding Category:
Research and Development
Activity Code:
Research Project (R01)
Purpose: The purpose of this notice of funding opportunity (NOFO) is to support research studies of two or more vaccine adjuvants (combination adjuvants) in order to understand the mechanisms by which they work in concert. All adjuvants considered must have previously demonstrated immune modulating activity. The long-term goal of this research program is to improve the rational design of vaccines by predicting the immune profile elicited by combination adjuvants.
Issuing Organization:
NIAID
Application Types Allowed:
New, Renewal
Release Date:
January 13, 2025
Expiration Date:
June 11, 2025
Clinical Trials:
Not Allowed
Interventions on Health and Healthcare Disparities on Non-Communicable and Chronic Diseases in Latin America: Improving Health Outcomes Across the Hemisphere (R01 - Clinical Trial Required)
Notice Number:
Funding Instrument:
Grant
Funding Category:
Research and Development
Activity Code:
Research Project (R01)
Purpose: The purpose of this Notice of Funding Opportunity (NOFO) is to support innovative and interdisciplinary research teams focused on clinical, health services, and/or community-based interventions that address health and healthcare disparities related to non-communicable and chronic diseases (NCDs) with the highest burden and mortality in Latin America and among U.S. Hispanics/Latinos. Multidisciplinary research teams would be expected to meaningfully collaborate with key partners that must include at least one PI or MPI from institutions in Latin America.
Issuing Organization:
NIMHD
Participating Organization(s):
NINR, ORWH
Application Types Allowed:
New, Resubmission, Revision
Release Date:
January 13, 2025
Expiration Date:
May 8, 2027
Clinical Trials:
Required
NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34 Clinical Trial Optional)
Notice Number:
Funding Instrument:
Cooperative Agreements
Funding Category:
Research and Development
Activity Code:
Planning Cooperative Agreement (U34)
Purpose: NIDDK supports investigator-initiated, high-risk multi-center (more than one center) clinical studies through a two-part process that may include an implementation planning cooperative agreement (U34). The U34 is designed to: 1) Permit early peer review of the rationale for the proposed clinical study; 2) Permit assessment of the design and protocol of the proposed study; 3) Provide support for the development of documents needed for the conduct of the study, including a manual of operations; and 4) Support the development of other essential elements required for the conduct of the clinical study. The proposed clinical study should be hypothesis-driven and focus on a disease in the mission of NIDDK. Consultation with NIDDK scientific staff is strongly encouraged prior to the submission of the U34 application.
Issuing Organization:
NIDDK
Application Types Allowed:
New, Resubmission
Release Date:
January 10, 2025
Expiration Date:
June 11, 2027
Clinical Trials:
Optional
Time-Sensitive Evaluation of Policies Affecting Health Behaviors and Chronic Disease Risk (R01-Clinical Trial Not Allowed)
Notice Number:
Funding Instrument:
Grant
Funding Category:
Research and Development
Activity Code:
Research Project (R01)
Purpose: This Notice of Funding Opportunity (NOFO) establishes an accelerated review/award process to support time-sensitive research to evaluate a new policy or program that is likely to influence obesity related behaviors (e.g., dietary intake, physical activity, or sedentary behavior) and/or weight outcomes in an effort to prevent or reduce obesity. This NOFO is intended to support research where opportunities for empirical study are, by their very nature, only available through expedited review and funding. All applications to this NOFO must demonstrate that the evaluation of an obesity related policy and /or program offers an uncommon and scientifically compelling research opportunity that will only be available if the research is initiated with minimum delay. For these reasons, applications in response to this time-sensitive NOFO are not eligible for re-submission. It is intended that eligible applications selected for funding will be awarded within 4 months of the application due date. However, administrative requirements and other unforeseen circumstances may delay issuance dates beyond that timeline.
Issuing Organization:
NIDDK
Participating Organization(s):
NCI, NICHD, ODP
Application Types Allowed:
New
Release Date:
January 10, 2025
Expiration Date:
January 12, 2028
Clinical Trials:
Not Allowed
Disseminating PCOR Evidence for Long COVID Care into Practice Through Up-to-Date Clinical Decision Support
Notice Number:
Funding Instrument:
Grant
Funding Category:
Research and Development
Activity Code:
Research Demonstration and Dissemination Projects (R18)
Purpose: The purpose of this is NOFO is to disseminate patient-centered outcomes (PCOR) evidence for Long COVID care into clinical practice through clinical decision support (CDS) that is consistently updated as best practices and new evidence emerge.
Issuing Organization:
AHRQ
Application Types Allowed:
New
Release Date:
January 10, 2025
Expiration Date:
March 19, 2025
Clinical Trials:
Optional
Single Source: Bench to Bassinet Congenital Heart disease Advancing New understanding in GEnomics Cohort (B2B CHANGE Cohort) Data Coordinating Center (U01 Clinical Trial Not Allowed)
Notice Number:
Funding Instrument:
Cooperative Agreements
Funding Category:
Research and Development
Activity Code:
Research Project--Cooperative Agreements (U01)
Purpose: The B2B Pediatric Cardiac Genomics Consortium (PCGC) (http://www.benchtobassinet.com/) will evolve to the B2B CHANGE Cohort (Congenital Heart disease Advancing New understanding in GEnomics). The B2B CHANGE Cohorts mission will be to conduct long-term clinical follow up on participants from the original PCGC Cohort, to perform deeper cohort phenotyping and to support investigators in applying for funding to conduct multi-center, collaborative ancillary studies to further understand how genetic variants relate to clinical outcomes. The Administrative Coordinating Center (ACC) will serve to lead and advance data and resource management and sharing, and coordinate critical data collection and participant outreach efforts at the clinical research sites. The ACC will work in a collaborative fashion with site PIs, as well as the broader congenital heart disease (CHD) research community.
Issuing Organization:
NHLBI
Application Types Allowed:
New
Release Date:
January 10, 2025
Expiration Date:
March 19, 2025
Clinical Trials:
Not Allowed
Multimodal Artificial Intelligence to Accelerate HIV Clinical Care (R01 Clinical Trial Optional)
Notice Number:
Funding Instrument:
Grant
Funding Category:
Research and Development
Activity Code:
Research Project (R01)
Purpose: This initiative will leverage cutting edge generative AI technology to augment existing narrow AI/ML approaches used in clinical care that will expand our capacity to address the dynamic, complex, and evolving HIV epidemic.
Issuing Organization:
NIMH
Participating Organization(s):
NIDA
Application Types Allowed:
New
Release Date:
January 10, 2025
Expiration Date:
March 28, 2025
Clinical Trials:
Optional